If I sort the OVA_cna file by mean cna expression it becomes apparent that many genes have identical measurements. For instance, (ATP8B3
KLF16,REXO1) all have identical measurements across patients. I've never analyzed CNA data before so I'm wondering if this is expected, or if maybe it's a result of normalization?
-Jeremy
Created by Jeremy Jacobsen jjacob_cub Hi Jeremy,
We acuqired the genomic data from CPTAC papers and TCGA firehose. The genes you mentioned share the same cytogenetic band 19p13.3, therefore we are not surprised the CNA measurement of these close regions are identical. Please feel free to make your own decision whether use them or not for your modeling.
Thanks,
Zhi