GSE106519

syn77114550

Created By Aditya Nath aditya.nath

doi: 10.1172/JCI95200
title: Expression data from human endothelial cells co-cultured with cancer associated fibroblasts
funder: NIH-NCI
series:
creator: Yeung Tsz Leung Sze Mok Samuel
license: CC-BY 4.0
species: Homo sapiens
studyId: syn9775595
subject:
ageGroup:
citation: Leung CS et al. (2018). Cancer-associated fibroblasts regulate endothelial adhesion protein LPP to promote ovarian cancer chemoresistance. J Clin Invest. 128(2):589-606. doi: 10.1172/JCI95200
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: Cancer associated fibroblasts (CAFs) have been shown to plays crucial roles in cancer progression. Although increasing evidence demonstrates that CAFs have important roles in modulating the aggressive phenotypes of cancer cells, their effects on the tumor vasculature remain underexplored. We co-cultured TIME human microvascular endothelial cells (MECs) with either primary human ovarian CAFs or normal ovarian fibroblasts (NFs) to evaluate the effects of CAFs on phenotypes of endothelial cells.
grantNumber: CA188388
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE106519
manifestation:
specimenCount: 5
yearProcessed: 2017
countryOfOrigin:
individualCount: 1
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA array
externalRepositoryUri: geo:GSE106519
includedInDataCatalog:

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