GSE107470

syn77114506

Created By Aditya Nath aditya.nath

doi: 10.1073/pnas.1714703115
title: Fenofibrate Prevents Skeletal Muscle Loss in Mice with Lung Cancer
funder: NIH-NCI
series:
creator: Goncalves Marcus
license: CC-BY 4.0
species: Mus musculus
studyId: syn7349770
subject:
ageGroup:
citation: Goncalves MD et al. (2018). Fenofibrate prevents skeletal muscle loss in mice with lung cancer. Proc Natl Acad Sci U S A. 115(4):E743-E752. doi: 10.1073/pnas.1714703115
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: The cancer anorexia cachexia syndrome is a systemic metabolic disorder characterized by the catabolism of stored nutrients in skeletal muscle and adipose tissue that is particularly prevalent in non-small cell lung cancer (NSCLC). Loss of skeletal muscle results in functional impairments and increased mortality. The aim of the current study was to characterize the changes in systemic metabolism in a genetically engineered mouse model of NSCLC. We show that a portion of these animals develop l...
grantNumber: CA210184
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE107470
manifestation:
specimenCount: 30
yearProcessed: 2017
countryOfOrigin:
individualCount: 30
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE107470
includedInDataCatalog:

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