GSE103990

syn77110759

Created By Aditya Nath aditya.nath

doi: 10.1016/j.cell.2018.03.017
title: Tumor evolution and drug response in patient-derived organoid models of bladder cancer
funder: NIH-NCI
series:
creator: Lee Suk Shen Michael
license: CC-BY 4.0
species: Homo sapiens
studyId: syn7349759
subject:
ageGroup:
citation: Lee SH et al. (2018). Tumor Evolution and Drug Response in Patient-Derived Organoid Models of Bladder Cancer. Cell. 173(2):515-528.e17. doi: 10.1016/j.cell.2018.03.017
dataType: gene expression
keywords: bladder
accessType: Open Access
contributor:
description: Bladder cancer is the fifth most prevalent cancer in the U.S., yet is understudied and relatively lacking in suitable models. Here we describe a biobank of patient-derived organoid lines that recapitulates the spectrum of human bladder cancer at the histopathological and molecular levels. Organoid lines can be established efficiently from patient biopsies, including from patients before and after disease recurrence, and are interconvertible with orthotopic xenografts. Notably, these organoid ...
grantNumber: CA193313
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE103990
manifestation:
specimenCount: 42
yearProcessed: 2017
countryOfOrigin:
individualCount: 42
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE103990
includedInDataCatalog:

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