GSE114725

syn77105707

Created By Aditya Nath aditya.nath

doi: 10.1016/j.cell.2018.05.060
title: Single-cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment 3' RNA Sequencing
funder: NIH-NCI
series:
creator: Azizi Elham Carr Ambrose Plitas George Cornish Andrew Konopacki Catherine Prabhakaran Sandhya Nainys Juozas Wu Kenmin Kiseliovas Vaidotas Setty Manu Choi Kristy Fromme Rachel Dao Phuong McKenney Peter Wasti Ruby Kadaveru Krishna Mazutis Linas Rudensky Alexander Pe’er Dana
license: CC-BY 4.0
species: Homo sapiens
studyId: syn7315805
subject:
ageGroup:
citation: Azizi E et al. (2018). Single-Cell Map of Diverse Immune Phenotypes in the Breast Tumor Microenvironment. Cell. 174(5):1293-1308.e36. doi: 10.1016/j.cell.2018.05.060
dataType: gene expression
keywords: CD45+ leukocytes
accessType: Open Access
contributor:
description: Knowledge of immune cell phenotypes in the tumor microenvironment is essential for understanding mechanisms of cancer progression and immunotherapy response. We created an immune map of breast cancer using single-cell RNA-seq data from 45,000 immune cells from eight breast carcinomas, as well as matched normal breast tissue, blood, and lymph node. We developed a preprocessing pipeline, SEQC, and a Bayesian clustering and normalization method, Biscuit, to address computational challenges inher...
grantNumber: CA209975
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE114725
manifestation:
specimenCount: 56
yearProcessed: 2018
countryOfOrigin:
individualCount: 56
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE114725
includedInDataCatalog:

GSE114725 page is loading…