GSE109309

syn77105434

Created By Aditya Nath aditya.nath

doi: 10.1371/journal.pbio.2005594
title: The mammalian decidual cell evolved from a cellular stress response
funder: NIH-NCI
series:
creator: Erkenbrack Eric Maziarz Jamie Wagner Gunter
license: CC-BY 4.0
species: Monodelphis domestica
studyId: syn7315810
subject:
ageGroup:
citation: Erkenbrack EM et al. (2018). The mammalian decidual cell evolved from a cellular stress response. PLoS Biol. 16(8):e2005594. doi: 10.1371/journal.pbio.2005594
dataType: gene expression
keywords: Endometrial stromal fibroblasts
accessType: Open Access
contributor:
description: Among animal species, cell types vary greatly in terms of number and kind. The broad range of number of cell types among species suggests that cell type origination is a significant source of evolutionary novelty. The molecular mechanisms giving rise to novel cell types, however, are poorly understood. Here we show that a novel cell type of eutherians mammals, the decidual stromal cell (DSC), evolved by rewiring an ancestral cellular stress response. We isolated the precursor cell type of DSC...
grantNumber: CA209992
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE109309
manifestation:
specimenCount: 15
yearProcessed: 2018
countryOfOrigin:
individualCount: 15
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE109309
includedInDataCatalog:

GSE109309 page is loading…