GSE116468

syn77102102

Created By Aditya Nath aditya.nath

doi: 10.1038/s41590-018-0208-x
title: The effect of cellular context on miR-155 mediated gene regulation in four major immune cell types (PolyA-Seq)
funder: NIH-NCI
series:
creator: Rudensky Alexander
license: CC-BY 4.0
species: Mus musculus
studyId: syn7315805
subject: C57BL/6J
ageGroup:
citation: Hsin JP et al. (2018). The effect of cellular context on miR-155-mediated gene regulation in four major immune cell types. Nat Immunol. 19(10):1137-1145. doi: 10.1038/s41590-018-0208-x
dataType: gene expression
keywords: C57BL/6J
accessType: Open Access
contributor:
description: Numerous microRNAs and their target mRNAs are co-expressed across diverse cell types. However, it is unknown whether they are regulated in a cellular context-independent or -dependent manner. Here, we explored transcriptome-wide targeting and gene regulation by miR-155, whose activation-induced expression plays important roles in innate and adaptive immunity. Through mapping of miR-155 targets using differential Argonaute iCLIP, mRNA quantification with RNA-Seq, and 3’UTR usage analysis using...
grantNumber: CA209975
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE116468
manifestation:
specimenCount: 39
yearProcessed: 2018
countryOfOrigin:
individualCount: 39
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE116468
includedInDataCatalog:

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