GSE121861

syn77101850

Created By Aditya Nath aditya.nath

doi: 10.1016/j.celrep.2018.10.047
title: Single cell sequencing of mouse syngeneic tumor models
funder: NIH-NCI
series:
creator: Kumar Manu Du Jinyan Raue Andreas Lauffenburger Douglas
license: CC-BY 4.0
species: Mus musculus
studyId: syn17084053
subject:
ageGroup:
citation: Kumar MP et al. (2018). Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics. Cell Rep. 25(6):1458-1468.e4. doi: 10.1016/j.celrep.2018.10.047
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: Tumor ecosystems are composed of multiple cell types that communicate by ligand-receptor interactions. Targeting ligand-receptor interactions, for instance with immune check-point inhibitors, can provide significant benefit for patients. However, our knowledge of which interactions occur in a tumor and how these interactions affect outcome is still limited. We present an approach to characterize communication by ligand-receptor interactions across all cell types in a microenvironment using si...
grantNumber: CA215798
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE121861
manifestation:
specimenCount: 24
yearProcessed: 2018
countryOfOrigin:
individualCount: 24
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE121861
includedInDataCatalog:

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