GSE126973

syn77092999

Created By Aditya Nath aditya.nath

doi: 10.1038/s41586-019-1324-y
title: Transcriptome analysis of various TOX+ and TOX- tumor-infiltrating CD8 T cells and in vitro TOX over-expressing T cells.
funder: NIH-NCI
series:
creator: Schietinger Andrea Scott Andrew Betel Doron Dündar Friederike Zumbo Paul
license: CC-BY 4.0
species: Mus musculus
studyId: syn7315805
subject: C57BL/6
ageGroup:
citation: Scott AC et al. (2019). TOX is a critical regulator of tumour-specific T cell differentiation. Nature. 571(7764):270-274. doi: 10.1038/s41586-019-1324-y
dataType: gene expression
keywords: C57BL/6
accessType: Open Access
contributor:
description: TOX is selectively expressed in tumor-infiltrating CD8 T cells however the role of TOX in peripheral CD8 T cells is not known. The two goals of this study are to elucidate transcriptional changes between TOX-sufficient and TOX-deficient tumor infiltrating CD8 T cells and to elucidate the molecular program induced by TOX overexpression in peripheral CD8 T cells.
grantNumber: CA209975
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE126973
manifestation:
specimenCount: 19
yearProcessed: 2019
countryOfOrigin:
individualCount: 19
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE126973
includedInDataCatalog:

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