GSE119270

syn77091979

Created By Aditya Nath aditya.nath

doi: 10.1038/s41590-019-0480-4
title: Ptpn2 regulates the generation of cytotoxic Tim-3+ CD8+ T cells and restrains anti-tumor immunity
funder: NIH-NCI
series:
creator: LaFleur Martin Yates Kathleen
license: CC-BY 4.0
species: Mus musculus
studyId: syn12051865
subject: C57BL/6
ageGroup:
citation: LaFleur MW et al. (2019). PTPN2 regulates the generation of exhausted CD8(+) T cell subpopulations and restrains tumor immunity. Nat Immunol. 20(10):1335-1347. doi: 10.1038/s41590-019-0480-4
dataType: gene expression
keywords: spleen C57BL/6
accessType: Open Access
contributor:
description: Cellular and transcriptional experiments demonstrate that deletion of Ptpn2 enhances CD8+ T cell responses to chronic viral infection and cancer.
grantNumber: CA225088
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE119270
manifestation:
specimenCount: 39
yearProcessed: 2018
countryOfOrigin:
individualCount: 39
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE119270
includedInDataCatalog:

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