GSE137710

syn77091543

Created By Aditya Nath aditya.nath

doi: 10.1016/j.cell.2019.09.035
title: Transcriptional basis of mouse and human dendritic cell heterogeneity revealed by single-cell profiling
funder: NIH-NCI
series:
creator: Brown Chrysothemis Gudjonson Herman Pritykin Yuri Deep Deeksha Lavallee Vincent-Phillippe Mendoza Alejandra Fromme Rachel Mazutis Linas Ariyan Charlotte Leslie Christina Pe'er Dana Rudensky Alexander
license: CC-BY 4.0
species: Homo sapiens Mus musculus
studyId: syn7315805
subject:
ageGroup:
citation: Brown CC et al. (2019). Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 179(4):846-863.e24. doi: 10.1016/j.cell.2019.09.035
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: Dendritic cells (DCs) play a critical role in orchestrating adaptive immune responses due to their unique ability to serve as a principal antigen-presenting cell type capable of initiating T cell responses. Classical dendritic cells have been divided into two subsets, cDC1 and cDC2, based on phenotypic markers and their distinct abilities to prime CD8 and CD4 T cells and direct their differentiation into effectors. Whilst the transcriptional features of the cDC1 subset have been well charact...
grantNumber: CA209975
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE137710
manifestation:
specimenCount: 6
yearProcessed: 2019
countryOfOrigin:
individualCount: 6
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE137710
includedInDataCatalog:

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