GSE136028

syn77091443

Created By Aditya Nath aditya.nath

doi: 10.1038/s41590-019-0544-5
title: TCR sequencing paired with massively parallel 3′ RNA-seq reveals clonotypic T cell signatures
funder: NIH-NCI
series:
creator: Tu Ang Gierahn Todd Monian Brinda Morgan Duncan Mehta Naveen Ruiter Bert Shreffler Wayne Shalek Alex Love J
license: CC-BY 4.0
species: Mus musculus
studyId: syn9773338
subject:
ageGroup:
citation: Tu AA et al. (2019). TCR sequencing paired with massively parallel 3' RNA-seq reveals clonotypic T cell signatures. Nat Immunol. 20(12):1692-1699. doi: 10.1038/s41590-019-0544-5
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: High-throughput 3′ single-cell RNA-sequencing (scRNA-seq) allows cost-effective, detailed characterization of individual immune cells from tissues. Current techniques, however, are limited in their ability to elucidate essential immune cell features, including variable sequences of T cell antigen receptors (TCRs) that confer antigen specificity. Here, we present a strategy that enables simultaneous analysis of TCR sequences and corresponding full transcriptomes from 3′-barcoded scRNA-seq samp...
grantNumber: CA217377
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE136028
manifestation:
specimenCount: 12
yearProcessed: 2019
countryOfOrigin:
individualCount: 12
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE136028
includedInDataCatalog:

GSE136028 page is loading…