GSE115501

syn77091019

Created By Aditya Nath aditya.nath

doi: 10.3390/cancers11121910
title: RNA sequencing on circulating tumor cells from prostate cancer patients
funder: NIH-NCI
series:
creator: Liss Michael
license: CC-BY 4.0
species: Homo sapiens
studyId: syn9773346
subject:
ageGroup:
citation: Liu YL et al. (2019). Spatial EGFR Dynamics and Metastatic Phenotypes Modulated by Upregulated EphB2 and Src Pathways in Advanced Prostate Cancer. Cancers (Basel). 11(12):. doi: 10.3390/cancers11121910
dataType: gene expression
keywords: circulating tumor cells from prostate cancer patients
accessType: Open Access
contributor:
description: Circulating tumor cells (CTCs) undergo considerable stress in the bloodstream. To understand the underlying phenomenon, we conducted single-cell genomic or transcriptomic analyses of primary tumor cells shed in urine and CTCs in blood of prostate cancer patients. Of more than four hundred focal genomic alterations analyzed, increased and decreased copy-numbers of 113 recurrent regions were found in CTCs relative to primary tumor cells. Tumor cells with these pre-existing genomic alterations c...
grantNumber: CA217297
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE115501
manifestation:
specimenCount: 136
yearProcessed: 2018
countryOfOrigin:
individualCount: 136
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE115501
includedInDataCatalog:

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