GSE117285

syn77077573

Created By Aditya Nath aditya.nath

doi: 10.1038/s41422-020-0334-5
title: Pattern of Extramammary Paget disease gene expression
funder: NIH-NCI
series:
creator: Song Yongli Yu Zhengquan
license: CC-BY 4.0
species: Homo sapiens
studyId: syn18145018
subject:
ageGroup:
citation: Song Y et al. (2020). The Msi1-mTOR pathway drives the pathogenesis of mammary and extramammary Paget's disease. Cell Res. 30(10):854-872. doi: 10.1038/s41422-020-0334-5
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: To further understand different gene expression of Extramammary Paget disease skin and normal skin, we have employed whole skin microarray expression profiling as a discovery platform to identify different genes with Extramammary Paget disease skin and normal skin.comparision with normal skin, upgene is 4572 in disease group, downgene is 6473. mTOR pathway, RAS pathway, PI3K-AKT pathway, IL6-JAK-Stat3 pathway and so on are activated, WNT Pathway is inhibited.
grantNumber: CA217378
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE117285
manifestation:
specimenCount: 8
yearProcessed: 2018
countryOfOrigin:
individualCount: 1
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA array
externalRepositoryUri: geo:GSE117285
includedInDataCatalog:

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