GSE132737

syn77077488

Created By Aditya Nath aditya.nath

doi: 10.1371/journal.pone.0233962
title: Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model
funder: NIH-NCI
series:
creator: Price Jessica Azizi Elham Parvani Jenny Shukla Priyanka Kim Seoyeon Naiche L Slack-Davis Jill Pe’er Dana Kitajewski Jan
license: CC-BY 4.0
species: Mus musculus
studyId: syn7315805
subject: ID8 IP2
ageGroup:
citation: Price JC et al. (2020). Notch3 signaling promotes tumor cell adhesion and progression in a murine epithelial ovarian cancer model. PLoS One. 15(6):e0233962. doi: 10.1371/journal.pone.0233962
dataType: gene expression
keywords: Ovarian surface epithelium ID8 IP2
accessType: Open Access
contributor:
description: High grade serous ovarian cancer (HGSC) is the most common and deadly type of ovarian cancer, largely due to difficulties in early diagnosis and rapid metastasis throughout the peritoneal cavity. Previous studies have shown that expression of Notch3 correlates with worse prognosis and increased tumorigenic cell behaviors in HGSC. We investigated the mechanistic role of Notch3 in a model of metastatic ovarian cancer using the murine ovarian surface epithelial cell line, ID8 IP2. Notch3 was act...
grantNumber: CA209975
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE132737
manifestation:
specimenCount: 8
yearProcessed: 2019
countryOfOrigin:
individualCount: 8
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE132737
includedInDataCatalog:

GSE132737 page is loading…