GSE130140

syn77073941

Created By Aditya Nath aditya.nath

doi: 10.1186/s13059-020-02152-7
title: Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation
funder: NIH-NCI
series:
creator: Fang Celestia Wang Zhenjia Ntziachristos Panagiotis Zang Chongzhi
license: CC-BY 4.0
species: Homo sapiens
studyId: syn7349742
subject: CUTLL1
ageGroup:
citation: Fang C et al. (2020). Cancer-specific CTCF binding facilitates oncogenic transcriptional dysregulation. Genome Biol. 21(1):247. doi: 10.1186/s13059-020-02152-7
dataType: chromatin activity gene expression
keywords: CUTLL1
accessType: Open Access
contributor:
description: The three-dimensional genome organization is critical for gene regulation and can malfunction in diseases like cancer. As a key regulator of genome organization, CCCTC-binding factor (CTCF) has been characterized as a DNA-binding protein with important functions in maintaining the topological structure of chromatin and inducing DNA looping. Among the prolific binding sites in the genome, several events with altered CTCF occupancy have been reported as associated with effects in physiology or ...
grantNumber: CA193419
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE130140
manifestation:
specimenCount: 92
yearProcessed: 2019
countryOfOrigin:
individualCount: 92
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: ATAC-seq bisulfite sequencing ChIP-seq HI-C RNA-seq
externalRepositoryUri: geo:GSE130140
includedInDataCatalog:

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