GSE128676

syn77073620

Created By Aditya Nath aditya.nath

doi: 10.1016/j.bbagrm.2020.194631
title: Genome-wide chromatin interactions identify characteristic promoter-distal loops
funder: NIH-NCI
series:
authors: Zhou Yufan Jin Victor
creator: Zhou Yufan Jin Victor
license: CC-BY 4.0
species: Homo sapiens
studyId: syn9773346
subject:
ageGroup:
citation: Yang Y et al. (2020). The 3D genomic landscape of differential response to EGFR/HER2 inhibition in endocrine-resistant breast cancer cells. Biochim Biophys Acta Gene Regul Mech. 1863(11):194631. doi: 10.1016/j.bbagrm.2020.194631
dataType: chromatin activity
keywords: immortalized breast epithelial cell line
accessType: Open Access
contributor:
description: We developed a novel computational model, HiSIF (Hi-C Significant Interacting Fragments), which uses a Poisson Mixture Model (PMM) with a power-law decay background. We compared its performance to some existing programs with publicly available Hi-C data, and then applied it to in situ Hi-C data in breast cancer sensitive and resistant cells.
grantNumber: CA217297
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE128676
manifestation:
specimenCount: 4
yearProcessed: 2019
countryOfOrigin:
individualCount: 4
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: HI-C
externalRepositoryUri: geo:GSE128676
includedInDataCatalog:

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