GSE137528

syn77073227

Created By Aditya Nath aditya.nath

doi:
title: ECM mediated FGF-induced estrogen receptor activity and therapy response
funder: NIH-NCI
series:
authors: Gilkes Daniele
creator: Gilkes Daniele
license: CC-BY 4.0
species: Homo sapiens
studyId: syn7349766
subject: MCF7
ageGroup:
citation:
dataType: gene expression
keywords: MCF7
accessType: Open Access
contributor:
description: We wanted to investigate the effects of stromal signaling on ER+ breast cancer cells as recent work implicates the tumor microenvironment in the acquisition of resistance to endocrine therapy. We desired to examine the effects of both coculture with fibroblasts, and 2.5D monoculture of breast cancer cells on decellularized, fibroblast-derived extracellular matrix scaffolds. We cultured MCF7 cells alone (Unc_#_Mono) or in coculture (Co_#) with BJ fibroblasts to examine stromal signalling on ER...
grantNumber: CA210173
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE137528
manifestation:
specimenCount: 10
yearProcessed: 2019
countryOfOrigin:
individualCount: 10
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE137528
includedInDataCatalog:

GSE137528 page is loading…