GSE134590

syn77069560

Created By Aditya Nath aditya.nath

doi:
title: Compartment-dependent chromatin interaction dynamics revealed by liquid chromatin Hi-C
funder: NIH-NCI
series:
creator: Belaghzal Houda Borrman Tyler Stephens Andrew Lafontaine Denis Venev Sergey Weng Zhiping Marko John Dekker Job
license: CC-BY 4.0
species: Homo sapiens
studyId: syn7349742
subject: K562
ageGroup:
citation:
dataType: chromatin activity
keywords: K562 The continuous cell line K-562 was established by Lozzio and Lozzio from the pleural effusion of a 53-year-old female with chronic myelogenous leukemia in terminal blast crises.
accessType: Open Access
contributor:
description: Chromosomes are folded so that active and inactive chromatin domains are spatially segregated to form a variety of sub-nuclear neighborhoods. Compartmentalization is thought to occur through polymer phase/microphase separation mediated by interactions between loci of similar type. The nature and dynamics of these interactions are not known. We developed liquid chromatin Hi-C to map the stability of associations between loci genome-wide. Before fixation and Hi-C, chromosomes are fragmented rem...
grantNumber: CA193419
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE134590
manifestation:
specimenCount: 34
yearProcessed: 2019
countryOfOrigin:
individualCount: 34
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: HI-C
externalRepositoryUri: geo:GSE134590
includedInDataCatalog:

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