GSE136910

syn77068490

Created By Aditya Nath aditya.nath

doi: 10.1161/CIRCULATIONAHA.119.041231
title: RNA Seq of Subcutaneous adipose tissue from endothelial-AGO1-knockout (EC-AGO1-KO) mice and wild-type (WT) littermates
funder: NIH-NCI
series:
creator: Qi Zhijie
license: CC-BY 4.0
species: Mus musculus
studyId: syn22115279
subject: C57BL/6
ageGroup:
citation: Tang X et al. (2020). Suppression of Endothelial AGO1 Promotes Adipose Tissue Browning and Improves Metabolic Dysfunction. Circulation. 142(4):365-379. doi: 10.1161/CIRCULATIONAHA.119.041231
dataType: gene expression
keywords: Subcutaneous adipose tissue C57BL/6
accessType: Open Access
contributor:
description: Purpose: to profile transcriptome changes due to EC-AGO1-deficiency Methods: Subcutaneous adipose tissue were harvested. RNA was extracted using TRIzol and library was prepared for sequencing. Results: We found genes involved in pathways promoting angiogenesis, browning, insulin sensitivity to be upregulated, and those promoting inflammation and fibrosis to be decreased in KO compared with WT mice. Conclusions:Our study represents the detailed analysis of Ago1 regulate transcriptomes in SAT b...
grantNumber: CA250046
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE136910
manifestation:
specimenCount: 9
yearProcessed: 2019
countryOfOrigin:
individualCount: 9
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE136910
includedInDataCatalog:

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