GSE133655

syn77063837

Created By Aditya Nath aditya.nath

doi: 10.1038/s41467-021-26604-1
title: In Vitro Transcription Recycling Assay Identifies PAF1 as a Driver of RNA Pol II Recycling
funder: NIH-NCI
series:
creator: Chen Zhong
license: CC-BY 4.0
species: Homo sapiens
studyId: syn9773346
subject: LNCaP-abl
ageGroup:
citation: Chen Z et al. (2021). Transcription recycling assays identify PAF1 as a driver for RNA Pol II recycling. Nat Commun. 12(1):6318. doi: 10.1038/s41467-021-26604-1
dataType: chromatin activity
keywords: LNCaP-abl prostate cancer cells
accessType: Open Access
contributor:
description: RNA Polymerase II transcriptional recycling is an underappreciated mechanism for which the required factors and contributions to overall gene expression levels are poorly understood. We describe an in vitro methodology facilitating unbiased identification of novel RNA Pol II transcriptional recycling factors and quantitative measurement of transcriptional output from recycled transcriptional components. Proof-of-principle experiments identified PAF1 complex components among recycling factors ...
grantNumber: CA217297
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE133655
manifestation:
specimenCount: 123
yearProcessed: 2019
countryOfOrigin:
individualCount: 123
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: ChIP-seq
externalRepositoryUri: geo:GSE133655
includedInDataCatalog:

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