GSE129455

syn77054162

Created By Aditya Nath aditya.nath

doi: 10.1158/2159-8290.CD-19-0094
title: Cross-species single-cell analysis of pancreatic ductal adenocarcinoma reveals cancer-associated fibroblasts expressing MHC class II
funder: NIH-NCI
series:
creator: Tuveson David Baker Lindsey
license: CC-BY 4.0
species: Mus musculus
studyId: syn7315802
subject:
ageGroup:
citation: Elyada E et al. (2019). Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts. Cancer Discov. 9(8):1102-1123. doi: 10.1158/2159-8290.CD-19-0094
dataType: gene expression
keywords:
accessType: Open Access
contributor:
description: This study used 10X Genomics, single-cell RNA-sequencing to examine the cell types present in the KrasLSL-G12D; Trp53LSL-R172H; Pdx1-Cre (KPC) mouse model for pancreatic ductal adenocarcinoma. The study analyzed tumors from 4 different mice. For each tumor, we performed flow sorting to isolate all viable cells, and to isolate a fibroblast-enriched population of cells for single-cell RNA-seq to determine the transcriptomes of individual cells in KPC pancreatic ductal adenocarcinoma tumors.
grantNumber: CA209997
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE129455
manifestation:
specimenCount: 8
yearProcessed: 2019
countryOfOrigin:
individualCount: 8
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq single-cell RNA-seq
externalRepositoryUri: geo:GSE129455
includedInDataCatalog:

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