GSE102542

syn77041016

Created By Aditya Nath aditya.nath

doi: 10.1038/s41467-023-36967-2
title: An epigenetic switch controls the expression of an alternative NR2F2 isoform that unleashes a pro-metastatic program in melanoma
funder: NIH-NCI
series:
creator: Davalos Veronica Esteller Manel
license: CC-BY 4.0
species: Homo sapiens
studyId: syn43447081
subject:
ageGroup:
citation: Davalos V et al. (2023). An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma. Nat Commun. 14(1):1867. doi: 10.1038/s41467-023-36967-2
dataType: genomic variants
keywords:
accessType: Open Access
contributor:
description: Metastatic melanoma develops once transformed melanocytic cells begin to de-differentiate into migratory and invasive melanoma cells with neural crest cell (NCC)-like and epithelial-to mesenchymal transition (EMT)-like features. However, it is still unclear how transformed melanocytes assume a metastatic melanoma cell state. Here, we define DNA-methylation changes that accompany metastatic progression in melanoma patients and discover Nuclear Receptor Subfamily 2 Group F, Member 2 – isoform 2...
grantNumber: CA263001
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE102542
manifestation:
specimenCount: 8
yearProcessed: 2017
countryOfOrigin:
individualCount: 1
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: methylation array
externalRepositoryUri: geo:GSE102542
includedInDataCatalog:

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