GSE102553

syn77040974

Created By Aditya Nath aditya.nath

doi: 10.1038/s41467-023-36967-2
title: RNA-sequencing of NR2F2-isoform 2 melanoma cellular models
funder: NIH-NCI
series:
creator: Davalos Veronica Hernando Eva
license: CC-BY 4.0
species: Homo sapiens
studyId: syn43447081
subject:
ageGroup:
citation: Davalos V et al. (2023). An epigenetic switch controls an alternative NR2F2 isoform that unleashes a metastatic program in melanoma. Nat Commun. 14(1):1867. doi: 10.1038/s41467-023-36967-2
dataType: gene expression
keywords: WM239-derived 113/6-4L melanoma cell line
accessType: Open Access
contributor:
description: Melanoma is a highly metastatic tumor type responsible of the large majority of the skin cancer-related deaths. Melanoma cells recapitulate the migratory and invasive nature of neural crest stem cells from which melanocytes arise. However, the mechanisms by which these developmental programs confer melanoma cells with more aggressive properties are not understood. Here we provide evidence for an epigenetically regulated developmental program that is aberrantly re-activated by melanoma cells t...
grantNumber: CA263001
diseaseFocus:
downloadType: Synapse Hosted
alternateName: GSE102553
manifestation:
specimenCount: 6
yearProcessed: 2017
countryOfOrigin:
individualCount: 6
visualizeDataOn:
dataUseModifiers:
conditionsOfAccess: No restriction
measurementTechnique: RNA-seq
externalRepositoryUri: geo:GSE102553
includedInDataCatalog:

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