Hello, Thank you very much for making this valuable data available to the scientific community. I have a question regarding the filtering process of the mutational data: beyond the germline filtering applied to the mutation data, is any additional filtering performed? I noticed that some panels reference hotspot regions in the data guide, so I was curious if there is any alignment or harmonization done between panels that assay more than hotspot regions (coding exons) and those focused only on hotspot regions? Thank you again for your assistance. Best regards, Maayan