The purpose of the study is to evaluate the safety and efficacy of ceftriaxone treatment in amyotrophic lateral sclerosis (ALS). Ceftriaxone is approved by the U.S. Food and Drug Administration (FDA) for treating bacterial infections but not for treating ALS. Also, ceftriaxone has not been given to people over a long period of time, such as months or years. The goals of this study are to evaluate the safety and effectiveness of ceftriaxone as a treatment for ALS, and to determine the safety and effectiveness of long-term use of the drug in people with ALS. Created By Ram Ayyala ram.ayyala
url: https://fair.dap.c-path.org/#/data/datasets/fv1_als1001_2025_02_26 title: Clinical Trial Ceftriaxone in Subjects With ALS sameAs: cpath:1796 source: Critical Path Institute creator: Massachusetts General Hospital species: Homo sapiens subject: amyotrophic lateral sclerosis keywords: ALS Amyotrophic Lateral Sclerosis disorder neurodegenerative placebo cephalosporin antibiotic motor neurons publisher: Critical Path Institute collection: ALS Knowledge Portal contributor: Massachusetts General Hospital (MGH)
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