Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors

syn68634225

Created By NF Service nf-osi-service

doi: 10.1073/pnas.2407745121
pmid: 39793045
program: NF-OSI
studyId: syn68634225
dataType: RNA-seq TMT quantitation
studyName: Hydroxychloroquine prevents resistance and potentiates the antitumor effect of SHP2 inhibition in NF1-associated malignant peripheral nerve sheath tumors
dataStatus: Available
initiative: DHART-SPORE Project 1
studyLeads: Sameer Farouk Sait Luis F Parada
studyStatus: Completed
diseaseFocus: Neurofibromatosis type 1
grantEndDate: 1751328000000
institutions: Memorial Sloan Kettering Cancer Center
fundingAgency: NIH-NCI
manifestation: MPNST
embargoEndDate: 1751328000000
grantStartDate: 1751328000000
resourceStatus: approved
studyFileviewId: syn68634236
alternateDataRepository: pride.project:PXD035998 pride.project:PXD035999 pride.project:PXD036000 geo:GSE283902
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