Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons (RNA-Seq)

syn67754663

Gene Expression Omnibus RNA-seq dataset profiling post-mortem middle frontal cortex samples from FTD and FTD-ALS cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126542
assay: RNA-seq
title: Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons, RNA-Seq
sameAs: geo:GSE126542
source: Gene Expression Omnibus
creator: Liu EY
disease: FTD FTD-ALS
species: Homo sapiens
cellType: NeuN+ neurons
dataType: transcriptomics
keywords: Frontotemporal Dementia Amyotrophic Lateral Sclerosis brain tissue sorted nuclei RNA-seq transcriptomics post-mortem tissue
CNSRegion: middle frontal cortex
studyType: experimental study
contributor: Edward Lee Lab – University of Pennsylvania
dataSubtype: bulk
isPostMortem: True
libraryLayout: paired-end
portalRelease: 2025.2
GEOSuperSeries: GSE126543
biospecimenType: brain tissue
individualCount: 7
biospecimenSubtype: sorted nuclei
acknowledgementStatement: syn64892175/wiki/633970
libraryPreparationMethod: NuGEN Ovation Ultralow Library System Kit

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