Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons (ATAC-Seq)

syn67751280

Gene Expression Omnibus ATAC-seq dataset profiling post-mortem middle frontal cortex samples from FTD and FTD-ALS cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE126541
assay: ATAC-seq
title: Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons, ATAC-Seq
sameAs: geo:GSE126541
source: Gene Expression Omnibus
creator: Liu EY
disease: FTD FTD-ALS
species: Homo sapiens
cellType: NeuN+ neurons
dataType: epigenomics
keywords: Frontotemporal Dementia Amyotrophic Lateral Sclerosis brain tissue sorted nuclei ATAC-seq epigenomics post-mortem tissue
CNSRegion: middle frontal cortex
contributor: Edward Lee Lab – University of Pennsylvania
libraryLayout: single-end
portalRelease: 2025.1
GEOSuperSeries: GSE126543
biospecimenType: brain tissue
individualCount: 14
biospecimenSubtype: sorted nuclei
acknowledgmentStatement: syn64892175/wiki/633970
acknowledgementStatement: syn64892175/wiki/633970

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