Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD (bulk RNA-seq)

syn67743547

Gene Expression Omnibus RNA-seq dataset profiling post-mortem dorsolateral prefrontal cortex and primary motor cortex samples from C9-ALS, C9-FTD, and Control cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE219278
assay: RNA-seq
title: Divergent impacts of C9orf72 repeat expansion on neurons and glia in ALS and FTD (bulk RNA-seq)
sameAs: geo:GSE219278
source: Gene Expression Omnibus
creator: Li J
disease: C9-ALS C9-FTD Control
species: Homo sapiens
cellType: neurons oligodendrocyte lineage cells other glia
dataType: transcriptomics
keywords: C9orf72+ Frontotemporal Dementia Amyotrophic Lateral Sclerosis brain tissue sorted nuclei RNA-seq transcriptomics post-mortem tissue
CNSRegion: dorsolateral prefrontal cortex primary motor cortex
studyType: experimental study
libraryLayout: paired-end
portalRelease: 2025.2
GEOSuperSeries: GSE219281
biospecimenType: brain tissue
individualCount: 114
biospecimenSubtype: sorted nuclei
acknowledgementStatement: syn64892175/wiki/633970

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