Truncated stathmin-2 is a marker of TDP-43 pathology in frontotemporal dementia

syn67733559

Gene Expression Omnibus RNA-seq dataset profiling post-mortem spinal cord tissue and brain tissue samples from lumbar spine, cervical spine, cerebellum, lateral motor cortex, frontal cortex, motor cortex, medial motor cortex, sensory cortex, occipital cortex, thoracic spine, temporal lobe cortex, and hippocampus collected from ALS, FTD, Control, Pre-fALS, Alzheimer's Disease, Parkinson's Disease, Other Neurological Disorders, and Other Motor Neuron Disease cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE153960
assay: RNA-seq
sameAs: geo:GSE153960
source: Gene Expression Omnibus
disease: ALS FTD Control Pre-fALS Alzheimer's Disease Parkinson's Disease Other Neurological Disorders Other Motor Neuron Disease
species: Homo sapiens
dataType: transcriptomics
keywords: Alzheimer's Disease Parkinson's Disease Other Neurological Disorders Other Motor Neuron Disease Frontotemporal Dementia Amyotrophic Lateral Sclerosis spinal cord tissue brain tissue RNA-seq transcriptomics post-mortem tissue
CNSRegion: lumbar spine cervical spine cerebellum lateral motor cortex frontal cortex motor cortex medial motor cortex sensory cortex occipital cortex thoracic spine temporal lobe cortex hippocampus
studyType: experimental study
contributor: NYGC ALS Consortium Target ALS
dataSubtype: bulk
isPostMortem: True
libraryLayout: paired-end
portalRelease: 2025.4
GEOSuperSeries: GSE137810
biospecimenType: spinal cord tissue brain tissue
individualCount: 478
acknowledgementStatement: syn64892175/wiki/633970
libraryPreparationMethod: KAPA Stranded RNA-Seq Kit with RiboErase

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