Unexpected similarities between C9ORF72 and sporadic forms of ALS-FTD suggest a common disease mechanism

syn67729513

Gene Expression Omnibus RNA-seq dataset profiling brain tissue samples from cerebellum collected from ALS, FTD, Control, Pre-fALS, Parkinson's Disease (PD), and Alzheimer's Disease (AD) cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE116622
assay: RNA-seq
sameAs: geo:GSE116622
source: Gene Expression Omnibus
disease: ALS FTD Control Pre-fALS Parkinson's Disease Alzheimer's Disease
species: Homo sapiens
dataType: transcriptomics
keywords: Parkinson's Disease (PD) Alzheimer's Disease (AD) Frontotemporal Dementia Amyotrophic Lateral Sclerosis brain tissue RNA-seq transcriptomics post-mortem tissue
CNSRegion: cerebellum Unknown
studyType: experimental study
contributor: NYGC ALS Consortium Target ALS
dataSubtype: bulk
isPostMortem: True Unknown
libraryLayout: paired-end
portalRelease: 2025.1
GEOSuperSeries: GSE137810
diseaseSubtype: PD AD
biospecimenType: brain tissue Unknown
participant_count: 75
acknowledgementStatement: syn64892175/wiki/633970
libraryPreparationMethod: KAPA Stranded RNA-Seq Kit with RiboErase

Unexpected similarities between C9ORF72 and sporadic forms of ALS-FTD suggest a common disease mechanism page is loading…