Abnormal RNA stability in amyotrophic lateral sclerosis

syn67713129

Gene Expression Omnibus BruChase-seq and Bru-seq dataset profiling fibroblasts and iPSC cells from Control, C9-ALS, and sporadic ALS cases.
Created By Aditya Nath aditya.nath

url: https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE115310
assay: BruChase-seq Bru-seq
title: Abnormal RNA stability in amyotrophic lateral sclerosis
cohort: C9-ALS sALS Healthy Control
sameAs: geo:GSE115310
source: Gene Expression Omnibus
creator: Tank EM
disease: Control ALS
species: Homo sapiens
cellType: fibroblasts iPSC
citation: doi:10.1038/s41467-018-05049-z
dataType: transcriptomics (nascent)
keywords: C9orf72+ Amyotrophic Lateral Sclerosis primary cell culture BruChase-seq Bru-seq transcriptomics (nascent)
CNSRegion:
studyType: experimental study
cohortType: Case-Control Healthy-Control
contributor: Barmada Lab - University of Michigan
study_count: 1
cohort_count: 3
libraryLayout: single-end
portalRelease: 2025.1
diseaseSubtype: C9-ALS sporadic ALS
biospecimenType: primary cell culture
participant_count: 60
acknowledgementStatement: syn64892175/wiki/633970

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