grant: UH3AG064706 study: Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation methods: syn68330917 program: ELITE project: ILO TGEN species: Cross-Species Mammalian studyKey: Gorbunova_CP_Transcriptomics studyName: Comparative transcriptomics reveals circadian and pluripotency networks as two pillars of longevity regulation studyWiki: syn66268111 accessReqs: syn27229419/wiki/630337 ackContext: syn27229419/wiki/622005 consortium: ELITE dataStatus: Available isFeatured: false isReleased: true studyFocus: Longevity dataTypeAll: Gene Expression metadataType: study isModelSystem: true studyAbstract: This cross-species study uncovers gene expression patterns linked to lifespan in 26 mammals. It reveals that long-lived species tend to upregulate genes involved in DNA repair and cell reprogramming, while short-lived species show higher expression of metabolic and inflammatory genes. The findings highlight circadian and pluripotency networks as key regulators of longevity. studyMetadata: syn68493777 acknowledgment: syn68330921 dataRestriction: Not Applicable modelSystemType: animal studyDescription: syn66268111 syn68330921 syn66271578 syn68493777 syn68330917
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