Hello, We are starting to think about approaches to tackle the challenges with background selection. We were wondering, in exons, if we will know which sites are synonymous and which ones are nonsynonymous (like we would in real popgen data). For the human scenarios based on exons in the human genome, can we assume the exon structure is the same as that in humans (the same synonymous and nonsynonymous sites)? Sincerely, Austin Daigle

Created by Austin Daigle austin.t.daigle
Yes, sounds good to me. Thank you!
Hello Austin, For the sweep challenges, we haven't annotated sites as synonymous or nonsynonymous, but we will for the demographic history challenges. For the sweep challenges, you can assume the same exon structure as humans. For the demographic history inferences, we wanted something more gene dense, so we're using Drosophila chromosomes (but not Drosophila parameters for demographic history and DFE). Does that answer your question? Best, Ryan

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