Dear @ULFEnCMICCAI2025Participants, We would like to share a few important updates regarding the ULF-EnC Challenge (MICCAI 2025): **Validation Re-Scoring with Masking:** As indicated in our challenge documentation, we have re-scored all validation submissions using masks that include both the brain and the skull region. This update ensures that it eliminates any potential bias from background intensities. We will use this to consider the final scoring. To avoid confusion, we have removed the total score from the leaderboard. Please refer to our challenge document (https://zenodo.org/records/15259777) for full details on the final scoring procedure and tie-breaking rules. **CMT Submission System Now Open:** The ULF-EnC Challenge CMT submission site is now live. Submission will be open from August 1st, and all teams are strongly encouraged to review the instructions ahead of time here: https://www.synapse.org/Synapse:syn65485242/wiki/633738 Thank you for your continued participation and contributions to the challenge! Best regards, ULF-EnC Challenge Organizing Team