Deep immunophenotyping reveals circulating activated lymphocytes in individuals at-risk for rheumatoid arthritis

syn64425850

Using data from the AMP RA.SLE Phase II PBMC CITE-seq and AMP RA.SLE PhaseII CyTOF datasets, investigators examined PBMC gene and protein expression patterns and systematically identified activated lymphocyte phenotypes in RA At-Risk individuals, along with immunophenotypic differences between different At-Risk subpopulations
Created By Jessica Vera jmvera

doi: 10.7303/syn64425850.4
assay: scRNASeq CITESeq CyTOF feature barcode sequencing
program: AMP RA/SLE
project: RA
dataType: transcriptomics multimodal proteomics cytometry
diagnosis: control RA At-Risk RA
ARKRelease: 2024.12.R1
dataSubtype: single-cell
datasetType: publication
programPhase: II
datasetStatus: released
datasetVersion: 5
biospecimenType: PBMCs
publicationSynID: syn64429482
associatedCodeURL: https://github.com/fanzhanglab/AtRiskRA_SingleCell
associatedDataset: syn63912719 syn52623570
libraryPrepMethod: 10x Chromium 3 GEX
datasetDescription: syn64425787
acknowledgmentStatement: syn26710600/wiki/619685

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