Dear Synapse Project Team / Data Contributors, I hope this message finds you well. I am a researcher working on medical AI and clinical decision support systems, and I am very interested in using this dataset for non-commercial academic research purposes. Specifically, my work focuses on developing and evaluating deep learning models using clinical and imaging data to improve understanding and prediction of disease-related outcomes. I would like to kindly ask for guidance on the following points: 1. What is the recommended process to request access to this dataset? 2. Are there specific steps (e.g., access request buttons, data use agreements, IRB/ethics documentation) that I should complete before downloading the data programmatically via the Synapse API? 3. Is the dataset permitted to be used for training and evaluating machine learning models in an academic research setting? I fully understand and respect that Sage Bionetworks is not the data contributor, and I am happy to follow all required procedures defined by the data owners and the Synapse governance framework. My goal is to ensure that the data are used ethically, legally, and in full compliance with the project’s terms. Thank you very much for your time and support. I would greatly appreciate any guidance or pointers to relevant documentation or contacts.