The chromatin landscape of pathogenic transcriptional cell states in rheumatoid arthritis

syn53650034

AMP RA Phase II synovium 10x Genomics scATAC-seq data from RA and OA control cases. Twenty-four chromatin classes were identified which are proposed to represent ‘superstates’ corresponding to multiple transcriptional cell states as described in Nature Communications https://doi.org/10.1038/s41467-024-48620-7.
Created By James Eddy jaeddy

assay: snATACSeq snRNASeq
program: AMP RA/SLE
project: RA
dataType: epigenomics transcriptomics multimodal
diagnosis: RA OA
ARKRelease: 2024.06.R1
dataSubtype: single-nucleus
datasetType: publication
programPhase: II
dbGapAccession: phs003417.v2.p1
biospecimenType: synovial tissue
publicationSynID: syn64429479
associatedCodeURL: https://github.com/immunogenomics/RA_ATAC_multiome/
libraryPrepMethod: 10x Chromium Next GEM Single Cell ATAC v1.1
datasetDescription: syn60548089
acknowledgmentStatement: syn26710600/wiki/619685

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