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title: Colony Forming Assays for NF1 MPNST Cell Lines funder: GFF creator: Raymond Mattingly license: https://creativecommons.org/licenses/by/4.0/ species: Homo sapiens Rattus norvegicus studyId: syn53185180 subject: NF1 MPNST drug screening RAS pathway inhibition cancer therapeutic approaches dataType: cellular physiology keywords: MPNST colony formation FTI lovastatin NF1 cell proliferation drug combination accessType: Public Access contributor: Robert Allaway description: Colony formation assay data from NF1 MPNST cell lines treated with farnesyltransferase inhibitors (FTI) and lovastatin combinations. This dataset includes assay results from multiple cell lines including S462TY, rat Schwann cells, and ST88-14. diseaseFocus: Neurofibromatosis type 1 manifestation: Malignant Peripheral Nerve Sheath Tumor (MPNST) dataUseModifiers: General Research Use measurementTechnique: cell proliferation croissant_file_s3_object: https://synapse-croissant-metadata.s3.us-east-1.amazonaws.com/Colony+forming+assays_syn53185351.2_datasetCollection_syn50913342_croissant.jsonld