Single Agent Screens of pNF Cell Lines

syn51914953

If you use this dataset, please cite the following publication: "Ferrer M, Gosline SJC, Stathis M, et al. Pharmacological and genomic profiling of neurofibromatosis type 1 plexiform neurofibroma-derived schwann cells. Sci Data. 2018;5:180106. Published 2018 Jun 12. doi:10.1038/sdata.2018.106.
Created By Anh Nguyet Vu avu

title: Single Agent Screens of pNF Cell Lines
funder: NTAP
series: None
creator: NF-OSI
license: UNKNOWN
species: Homo sapiens Mus musculus
studyId: syn4939906
dataType: drug screen
keywords: drug screen single agent pNF MIPE 4.0 NF1
accessType: Public Access
contributor: NF-OSI
description: Single agent screen of the MIPE 4.0 library of approx. 1912 small molecules against 9 different cell-lines (5 NF1 nullizygous, 1 carrier, 2 normal, and 1 control) with diverse modes of action, and the generation of single agent viability results for each cell line to ID ~40 top hits (with highest potency and efficacy)
diseaseFocus: Neurofibromatosis type 1
versionLabel: croissant update
fundingAgency: NTAP
manifestation: Plexiform Neurofibroma
specimenCount: 11
yearProcessed: 2015
yearPublished: 2023
versionComment: Annotated with croissant_file_s3_object
countryOfOrigin: Unknown
individualCount: 11
dataUseModifiers: General Research Use
measurementTechnique: compound screen
includedInDataCatalog: https://www.synapse.org/DataCatalog:0
croissant_file_s3_object: https://synapse-croissant-metadata.s3.us-east-1.amazonaws.com/Single+Agent+Screens+of+pNF+Cell+Lines_syn51914953.4_datasetCollection_syn50913342_croissant.jsonld

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