doi: https://www.doi.org/10.7303/syn26004582 event: Hack for Rare 2021 summary: Plexiform neurofibromas (PN) are congenital tumors initiated by the loss of function of the Nf1 gene in children and young people. PN cell lines-based drug screen serves as an efficient way to identify the potential drug candidates. However, NF1-associated tumors easily develop drug resistance and relapse after treatment withdrawal. Drug combination may benefit the patients significantly by enhancing the inhibitory effects, reducing the single drug-related side effects. onSynapse: syn26004582 initiative: 2021 Hack for Rare studyLeads: 3332479 3430741 studyStatus: Completed diseaseFocus: Neurofibromatosis type 1 fundingAgency: CTF tab1wikipointer: syn26004582/wiki/611841 acknowledgementStatements: If you use data/concepts from this hackathon project in a publication or talk, please acknowledge the authors of this hackathon project. In addition, please acknowledge the Children's Tumor Foundation and NF Data Portal using the following statement: "The results published here are in whole or in part based on data/concepts made available through the NF Open Science Initiative and CTF Hack for Rare 2021." syn26015385 syn26008150 syn26008153 syn26017872 syn26008191 syn26010950 syn26010951 syn26010952 syn26010953 syn26015384 syn26008158 syn26010502
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