Hello,
I'd like to verify whether sex was regressed out of this dataset
https://www.synapse.org/#!Synapse:syn8456719
Thanks
Annat
Created by Annat Haber annat22 Hi @annat22,
That would definitely be clearer, we are working on another version of the normalization software currently which will incorporate this. In the current generation the line:
```Using following covariates in the final model: Batch, Sex, RINcontinuous, PCT_CODING_BASES, PCT_INTERGENIC_BASES, pmi, PCT_INTRONIC_BASES, age_death as fixed effects```
Indicates model covariates.
Thanks! That's helpful.
It would be good to have the covariates explicitly listed here
https://www.synapse.org/#!Synapse:syn8456629
Under the heading
"Adjust data with covariates for Network Analysis"
Currently it only says
"Identified covariates are regressed out from the expression matrix for network analysis" Hi @annat22
Yes, in line 422 of the [script denoted within the file provenance](https://github.com/th1vairam/ampad-DiffExp/blob/bd9766224c2d1515586c9377db7e08a6cb62bcc9/gene_level_analysis/ROSMAP_geneLevel.Rmd#L442), both Sex and Batch were selected as covariates for normalization.
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