Hello!
I was wondering if the single-cell RNA-seq data in microglia along with genotypes are available from the Olah et al. paper. The link to synapse is provided in the manuscript, but I can't seem to find it here.
Thank you,
Gloriia
Created by novikg Hi @novikg
The data described in the biorxiv manuscript will be released once the paper has been accepted. I suggest requesting membership [in this team](https://www.synapse.org/#!Team:3372003). Team members receive updates about data releases.
Best,
Mette Mette,
Wonderful, thank you!
I see, it is the single cell microglia you are looking for not the bulk tissue. We will follow up with the author and let you know
Hello, Mette!
I think the data you are referring to is from this paper, not the one I am looking for:
https://www.nature.com/articles/s41467-018-02926-5.pdf
Here they reference the link you have mentioned.
Should I contact the authors to ask?
Thanks,
Gloriia Hi @novikg - I believe this is the data you are looking for: https://www.synapse.org/#!Synapse:syn11468526
If you are on the page linked in the paper and scroll down you will see links to data generated for each assay from the ROSMAP cohort including the Microglia RNAseq. Note that data access requires the agreement to terms in this DUC. See instructions here: https://www.synapse.org/#!AccessRequirements:ID=syn11468526&TYPE=ENTITY
Best,
Mette Anna,
Thank you for the quick response!
Here is the reference:
Olah, M., Menon, V., Habib, N., Taga, M., Yung, C., Cimpean, M., ... & Hyman, B. T. (2018). A single cell-based atlas of human microglial states reveals associations with neurological disorders and histopathological features of the aging brain. bioRxiv, 343780.
The reference just in case:
https://www.biorxiv.org/content/biorxiv/early/2018/06/11/343780.full.pdf
Thank you,
Gloriia Hello,
Could you please provide the complete reference for the paper?
Thank you!
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