My question concerns the data deposited in folder: syn21638690.
Is it ok to use this data as is? Do I need to correct for density, etc.?
No correction method was mentioned anywhere.
What are the units of value?
Created by Momoka Tsuneyoshi momoca33 Hi @momoca33,
This synapse ID points to the raw intensities with some minimal correction, as described in the last paragraph of the methods in the [wiki](syn21347564) for the TMT proteomics (be sure to click "Show More" for the full text, and the cited papers will provide further details). If you want to use the mean-centered, corrected matrix used in the paper, you can find it [here](syn24983526), which is stored in the MSBB project folder in the AD Knowledge Portal and should have all the samples from the St Judes/Banner project in it. You can also upload the [TMT assay metadata](syn21893060) which corresponds to this matrix for batch information.
I hope that helps,
Laura