Hi,
I assume that before analysis peptides all somatic SNVs were identified in all six samples. Would it be possible to get a statistics on found mutations? Specifically I'm interested in the frequency of these mutations per patient.
Thank you!
Created by alex.maslov Hello Alex,
Hope you are doing well after researching the SNV's six samples. This is what I have acquired.
**Identify SNVs**: Use bioinformatics tools to identify somatic SNVs in your samples.
**Calculate Variant Allele Frequency (VAF):** Determine the frequency of each SNV in each sample.
**Aggregate Data**: Compile the VAF data for each patient to get an overall picture of mutation frequency
Let me know if you need any more help. Or if you want to set up a 1 on 1 meeting regarding this.
Sincerely,
Krishna