Hyejin Park fourmodern

• Research Experiences ➢ Molecular Modeling and Simulation: Protein Structure Modeling, In Silico Protein Design, Molecular Dynamics, Molecular structural simulation applied Monte Carlo method, Molecular docking, Molecular simulation by applied Monte Carlo Method, QSAR using machine learning method. • GPCR modeling, Kinase inhibitor profiling • Development of automated protein design program using Visual C++ and fortran • Protein structure modeling (DCAF1) and simulation • Hepatotoxicity prediction system and metabolite prediction system ➢ Biological Sequence Analysis: Phylogenetic Model using Bayesian Inference (using Markov Chain Monte Carlo), Motif search, Gene Expression Data analysis(gene set and pathway), RNA-seq Analysis, Connectivity Map analysis for Drug Repositioning • Toxicogenomic data analysis • EPA ToxCast data analysis • Connectivity Map analysis for Drug Repositioning ➢ Mass Spectrometry: Processing FTICR raw data, De Novo Protein Sequencing, Natural Product Identification, Metabolomic analysis using mass spectrometry profiling • Development FTICR raw data processing program for de novo protein sequencing using Visual C++,.Net framework and MySQL • Development natural product identification system using Java, Python, Pipeline Pilot and Oracle database • Skills ➢ Software: • Bioinformatics: R, SAS, Mr.Bayes, Pipeline Pilot, RapidMiner, Ingenuity pathway analysis (IPA), Gene Set Enrichment Analysis (GSEA) • Molecular modeling: Discovery Studio, Sybyl, Pymol, Modeler and CCP4 package • Molecular dynamics: Charmm, Amber, Gromacs, NAMD • Mass spectrometer program: openMS, Mascot, XCMS ➢ Programming • Language: Visual C++, Fortran, Perl, Python (Scipy and Numpy), Java • UML, Object-oriented analysis, Test-Driven Development • Basic SQL query for MySQL and Oracle database • Linux system administration ➢ Statistical Method • Machine learning method: PLS, MLR, ANN, SVM • Stochastic process and Bayesian inference (Markov Chain Monte Carlo Method)

Gwanak-gu, Seoul, Korea

Principal Researcher

Biotechnology

MediCoGem Inc.

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